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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FES All Species: 18.18
Human Site: S175 Identified Species: 40
UniProt: P07332 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07332 NP_001996.1 822 93497 S175 A K D K Y V R S L W K L F A H
Chimpanzee Pan troglodytes XP_001169365 822 93450 S175 A K D K Y V R S L W K L F A H
Rhesus Macaque Macaca mulatta XP_001093848 823 93241 S175 A K D K Y V R S L W K L F A H
Dog Lupus familis XP_851836 820 93016 S173 A K D K Y V R S L W K L F A H
Cat Felis silvestris
Mouse Mus musculus P16879 822 93760 S175 A K D K Y V R S L W K L F A H
Rat Rattus norvegicus P09760 323 37086
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512215 821 94492 K173 K A K D R Y D K V T M K L H I
Chicken Gallus gallus Q8JH64 657 75860 G108 F Q V V Y D E G P L Y V F S P
Frog Xenopus laevis NP_001085865 822 94618 N179 A K E K Y V K N T W K L H A L
Zebra Danio Brachydanio rerio XP_693576 842 96630 K174 K A R E R Y D K A T M K L H N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18106 1325 150245 K175 K L D D V R D K Y Q K A C R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.5 94 N.A. 90.6 26.2 N.A. 51.9 24.7 64.5 50.2 N.A. 27.6 N.A. N.A. N.A.
Protein Similarity: 100 100 98.1 97.1 N.A. 95.2 32.5 N.A. 69.8 41.7 80.7 66.7 N.A. 41.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 0 13.3 60 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 0 N.A. 6.6 33.3 80 13.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 55 19 0 0 0 0 0 0 10 0 0 10 0 55 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 55 19 0 10 28 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 10 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 55 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 19 46 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 28 55 10 55 0 0 10 28 0 0 64 19 0 0 10 % K
% Leu: 0 10 0 0 0 0 0 0 46 10 0 55 19 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % P
% Gln: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 10 0 19 10 46 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 0 0 0 0 46 0 0 0 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 19 0 0 0 0 0 % T
% Val: 0 0 10 10 10 55 0 0 10 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 55 0 0 0 0 0 % W
% Tyr: 0 0 0 0 64 19 0 0 10 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _